The Directorate of Food and Drugs Administration, Government of Goa was established in November’ 1991 with its office functioning from the building premises at Campal, Panaji – Goa.  Thereafter the office premises was shifted and functioned from the Old Goa Medical Complex at Panaji – Goa; until October 2003 and thereafter  the Directorate functioned from the Old IPHB Complex at Altinho, Panaji – Goa until  February 2014.

Presently, the Directorate now functions from the Directorate of Food and Drug Administration, 'Dhanwantari', Opposite Shrine of the Holy Cross, Bambolim - Goa  403202.

Prior to the establishment of an independent Food and Drugs Administration, the Directorate, was functioning as an office of the Drugs Controller as one of the various units under the Directorate of Health Services at Campal and was entrusted to handle all food and drugs related legislation.
The Directorate functions with its one wing involved in the administration and drugs/food activities through its office situated at Bambolim; whilst its Food and Drugs Laboratory functions from its independent building located at Bambolim.